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Nestorius and his followers fled from persecution in the Byzantine Empire after the Council of Ephesus 431 banned him and his teachings. They migrated to Persia and from there launched one of the most significant missionary movements. By the end of the 8th century they had spread to China and from Central Asia through Afghanistan to India, probably becoming the most numerous church in the world by the 9th century.
However, the Mongol invasions and the consolidation of Islam throughout these areas have now reduced this church to its present-day numbers of around 100,000.