Cone-shaped outgrowth of the vertebrate brain. In some lower vertebrates, it develops a rudimentary lens and retina, which show it to be derived from an eye, or pair of eyes, situated on the top of the head in ancestral vertebrates. In fishes that can change colour to match their background, the pineal perceives the light level and controls the colour change. In birds, the pineal detects changes in daylight and stimulates breeding behaviour as spring approaches. Mammals also have a pineal gland, but it is located deeper within the brain. It secretes a hormone, melatonin, thought to influence rhythms of activity, especially the
circadian rhythm. In humans, it is a small piece of tissue attached by a stalk to the rear wall of the third ventricle of the brain.
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