In vertebrates, a group of muscle cells in the wall of the heart that contracts spontaneously and rhythmically, setting the pace for the contractions of the rest of the heart. The pacemaker's intrinsic rate of contraction is increased or decreased, according to the needs of the body, by stimulation from the
autonomic nervous system. The term also refers to a medical device implanted under the skin of a patient whose heart beats inefficiently. It delivers minute electric shocks to stimulate the heart muscles at regular intervals and restores normal heartbeat.
The latest pacemakers are powered by radioactive isotopes for long life and weigh no more than 15 g/0.5 oz.
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