Pebblelike, insoluble accretion formed in the human gall bladder or bile ducts from cholesterol or calcium salts present in bile. Gallstones may be symptomless or they may cause pain, indigestion, or jaundice. They can be dissolved with medication or removed, either by means of an endoscope or, along with the gall bladder, in an operation known as cholecystectomy.
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