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The amount of atovaquone in the blood may be reduced by the following medicines and these could make it less effective at preventing and treating malaria:
- metoclopramide
- rifampicin and rifabutin (these medicine are not recommended for people taking Malarone)
- tetracycline.
Atovaquone may decrease the blood level of the anti-HIV medicine indinavir.
The antacid magnesium trisilicate may decrease the absorption of proguanil from the gut if it is given at the same time of day. If both medicines are needed their doses should be separated by at least three hours.
Other medicines containing the same active ingredients
| Malarone |