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The following medicines should be avoided in people taking memantine, as they act in the same way as this medicine and may therefore increase the chances of side effects:
- amantadine
- dextromethorphan
- ketamine.
Phenytoin should be used with caution for the same reason.
Memantine may alter the effects of the following medicines. If any of these are taken in combination with memantine your doctor may need to alter the doses of either medicine:
- levodopa and other dopamine agonists for Parkinson's disease, eg ropinirole, pramiprexole, apomorphine, bromocriptine
- anticholinergic medicines for movement disorders such as Parkinson's disease (eg procyclidine) or intestinal cramps (eg atropine)
- barbiturates, eg amobarbital, phenobarbital
- antipsychotic medicines
- dantrolene
- baclofen
- cimetidine
- ranitidine
- procainamide
- quinidine
- quinine
- nicotine
- hydrochlorothiazide.
This medicine may possibly enhance the effect of oral anticoagulant medicines such as warfarin. The manufacturer recommends that people taking this medicine in combination with an oral anticoagulant should have their blood clotting time (INR) closely monitored.
Other medicines containing the same active ingredient
There are currently no other medicines available in the UK that contain memantine as the active ingredient.
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