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How does it work?Elidel cream contains the active ingredient pimecrolimus, which is a type of medicine called a skin-selective inflammatory cytokine inhibitor. It is used to decrease skin inflammation in eczema.
Pimecrolimus is absorbed into the skin, where it works by blocking the production of inflammatory chemicals called cytokines. These are produced by white blood cells in the skin as part of the body's immune response to allergy or irritation, and are part of a cascade of events in the skin that results in the irritated area becoming inflamed - red, swollen and itchy.
As pimecrolimus stops the white blood cells in the skin from producing cytokines, it reduces inflammation in the skin.
Pimecrolimus cream is used to reduce the inflammation of the skin seen in eczema (atopic dermatitis). This relieves the symptoms of this condition, such as redness and itching.
Pimecrolimus is used for the short-term relief of eczema symptoms, and as intermittent treatment in the long-term management of eczema. The cream should be applied at the first signs of a flare-up of eczema (redness and itching of the skin), as this can help prevent progression to more severe flare-ups. Continuous long-term use of the cream should be avoided.
What is it used for?
- Mild to moderate eczema in adults and children aged two years and over, who are not responsive to, or intolerant of, conventional treatments such as topical corticosteroids.
Warning!
- This medicine is for external use only.
- Avoid contact of this medicine with the eyes, and areas of skin lining the body cavities (mucous membranes), eg inside the mouth and nose. If this medicine does accidentally come into contact with these areas it should be thoroughly wiped off and/or rinsed off with water.
- The cream should be applied thinly, as directed, to affected areas of skin only, until the symptoms clear. If there is no improvement in the skin after six weeks treatment, or if the skin gets worse, you should consult your doctor.
- Wash your hands thoroughly after applying this medicine, unless the hands are the area being treated.
- You should not cover the area being treated with airtight dressings such as bandages or other dressings, including nappies, as these will enhance the absorption of the medicine into the body and may increase the risk of adverse effects.
- This cream may cause skin reactions at the site of application, such as a feeling of warmth and/or a burning sensation. These reactions are usually mild and short-lived.
Consult your doctor if you experience a more severe reaction after applying this cream.
- On rare occasions, people using this medicine have experienced symptoms such as skin flushing, rash, burning, itching or swelling shortly after drinking alcohol.
- There may be an increased risk of skin infections such as severe herpes simplex infection (eczema herpeticum) in people using this medicine. If your skin becomes infected during treatment you should consult your doctor, as you may need to stop using this medicine until the infection has cleared.
- You should not receive light treatment, such as PUVA, or other UV light treatment, while using this medicine. You should also avoid using sun beds, and minimise exposure of your skin to sunlight by using sunscreens, wearing appropriate clothing to protect the skin when outside, and minimising time spent in the sun.
Not to be used in
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- Children under two years of age
- Allergy to macrolactam compounds such as tacrolimus, sirolimus or ciclosporin
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Infected eczema or dermatitis
- Areas of skin affected by viral infections, such as cold sores (herpes simplex) or chicken pox (herpes zoster)
- Areas of skin affected by cancerous or potentially cancerous growths
- People with an underactive immune system, for example due to a condition present from birth, certain diseases, or treatment with certain medicines eg (immunosuppresants, chemotherapy)
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Pregnancy
- This medicine is not recommended for use in people with genetic skin defects such as Netherton's syndrome, or people with intense widespread reddening of the skin (erythroderma), where there may be increased absorption of the medicine into the bloodstream.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- The safety of this medicine during pregnancy has not been established, therefore it should not be used by pregnant women. Seek medical advice from your doctor.
- It is not known if this medicine passes into breast milk, however, this is unlikely because only minimal amounts of the medicine are absorbed into the body through the skin. It should be used with caution in women who are breastfeeding and only if the potential benefits to the mother outweigh any potential risks to the nursing infant. Seek medical advice from your doctor.
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