Micropyrin

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

- Indigestion (dyspepsia)
- Stomach or intestinal discomfort
- Worsening of asthma
- Allergic reactions such as skin rash, swelling of the lips, tongue and throat (angioedema) or narrowing of the airways (bronchospasm)
- Ulceration or bleeding of the stomach or intestines

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

If you are taking any other medicines you should check with your pharmacist before taking this one to ensure that the combination is safe.

People taking anticoagulant medicines used to prevent the blood clotting, eg warfarin, should not take aspirin to relieve pain or inflammation. This is because the higher doses of aspirin used for pain relief can irritate the stomach lining, as well as increasing the effects of warfarin, both of which increase the likelihood of bleeding. Lower doses of aspirin used for a blood-thinning effect are safer, but should only be used by people taking anticoagulants such as warfarin on the advice of a doctor.

There may be an increased risk of bleeding if aspirin is taken with other 'blood-thinning' (antiplatelet) medicines such as clopidogrel or ticlopidine.

Aspirin reduces the rate at which the body can remove the medicine methotrexate. The two should not usually be used together.

There is an increased risk of side effects if aspirin is taken with other non-steroidal anti-inflammatory drugs (NSAIDs), eg ibuprofen, diclofenac, indometacin. For this reason, aspirin should not be taken with any other NSAID. Low-dose aspirin used for anti-blood-clotting purposes is an exception to this, but should only be used with other NSAIDs on the instruction of a doctor.

There may be an increased risk of bleeding or ulceration of the stomach or intestines if aspirin is taken with corticosteroids, eg prednisolone, dexamethasone.

There may be an increased risk of side effects if aspirin is taken with acetazolamide.

Micropyrin tablets have a special 'enteric coating' that is designed to stop the aspirin from irritating the stomach. Antacids (indigestion remedies) should not be taken at the same time of day as Micropyrin tablets because they allow this special coat to dissolve.

Other medicines containing the same active ingredient

Alka rapid crystals	Angettes 75	Aspro clear
Caprin	Caprin	Disprin
Disprin direct	Maximum strength aspro clear	Nu-seals
Nu-seals	POSTMI 75

Aspirin tablets, dispersible tablets, enteric-coated tablets and suppositories are also available without a brand name, ie as the generic medicine.

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