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Dovobet ointment

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How does it work?

Dovobet ointment contains two active ingredients, betamethasone dipropionate and calcipotriol hydrate.

Calcipotriol is a medicine that is a derivative of vitamin D. When applied to the skin it works by reducing the production of skin cells.

In psoriasis, the scaling and thickening of the skin and the appearance of raised plaques are the result of excessive skin cell production in this disease. Calcipotriol reduces the excessive skin cell production and helps improve these symptoms of psoriasis.

Betamethasone is a type of medicine called a corticosteroid. Corticosteroids are medicines used for reducing inflammation. Skin inflammation in psoriasis occurs due to the irritation of the skin, and is caused by the release of various substances important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful.

When betamethasone is applied to the skin it works by acting inside the cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch. Betamethasone is a potent corticosteroid.

The combination of medicines in this ointment is used to treat stable plaque psoriasis. The ointment should be applied once a day, initially for four weeks. If your psoriasis gets worse again after you stop treatment, the medicine can used for longer to keep the psoriasis under control. However, repeated or prolonged treatment must only be used on the advice and under the supervision of your doctor.

What is it used for?

- Stable plaque psoriasis

Warning!

- This medicine is for external use only.
- The ointment should be applied thinly and evenly to the affected area(s).
- Wash your hands after each application, unless you are treating psoriasis on your hands. Avoid accidentally transfering the ointment to the scalp, face, mouth or eyes.
- You should not use more than 15g of ointment in one day and more than 100g in one week, and the treated area of skin should not make up more than 30 per cent of the body surface.
- If corticosteroids are used long-term, on large areas of skin, raw skin, skin folds, or under airtight dressings they are absorbed into the body more. This increases the risk of local side effects such as skin thinning, and those on other parts of the body, such as a decrease in the production of natural hormones by the adrenal glands. Do not use this medicine on large areas of damaged skin, under dressings, or in skin folds (eg armpits or under breasts), unless told to do so by your doctor.
- Consult your doctor if your skin becomes infected during treatment, as you may need to stop using this medicine and start treatment with antibiotics.
- People using this medicine to treat psoriasis should have regular check-ups with their doctor.

This is because although corticosteroids may be useful for psoriasis in the short-term, they can sometimes make psoriasis worse, and may cause the condition to relapse into generalised pustular psoriasis after the treatment is stopped.

Use with caution in

.

- Diabetes
- High levels of calcium in the blood (hypercalcaemia)

Not to be used in

- Disorders of calcium metabolism in the body
- Severe liver disease
- Severely decreased kidney function
- Guttate psoriasis
- Exfoliative psoriasis
- Erythrodermic psoriasis
- Pustular psoriasis
- Acne vulgaris
- Chronic inflammatory disorder of the facial skin (acne rosacea)
- Inflammatory rash around the mouth (perioral dermatitis)
- Itching of the anus or genitals
- Bands of thin, wrinkled skin commonly found on the abdomen, thighs or buttocks following puberty or pregnancy (stretch marks/striae atrophicae)
- Dryness and fish skin-like scaling of the skin (ichthyosis)
- Skin with fragile veins
- Thin, easily damaged skin (atrophic skin)
- Ulcerated areas of skin
- Wounds
- Skin infected with parasites, eg scabies
- Skin infected with viruses (eg Herpes simplex, chickenpox), fungi (eg thrush, ringworm, athlete's foot) or bacteria (eg impetigo)
- Skin sores caused by tuberculosis
- Skin sores caused by syphilis.
- This medicine is not recommended for children and adolescents under eighteen years of age.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

- This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than any possible risk to the foetus. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings, or for prolonged periods of time. Consult your doctor for further information.
- This medicine should be used with caution by women who are breastfeeding. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings or for prolonged periods of time. If it is applied to the breasts it should be washed off carefully before breastfeeding and then reapplied afterwards. Seek medical advice from your doctor.

Label warnings

- This medication is to be spread thinly and sparingly on the skin.



The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care or attention by a qualified practitioner. The materials in this web site cannot and should not be used as a basis for diagnosis or choice of treatment. Conditions for use Powered by netdoctor
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