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Regurin

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Health Centres - Regurin



How does it work?

This medicine contains the active ingredient trospium chloride, which is a type of medicine called an anticholinergic. It is used to treat an unstable bladder. Trospium works by blocking cholinergic receptors that are found on muscle cells in the wall of the bladder. Normally, a natural body chemical called acetylcholine acts on these receptors, under the body's control, and this causes the bladder muscle to contract and the bladder to empty. Sometimes the bladder muscle can contract uncontrollably, causing the bladder to empty too frequently or unexpectedly. As trospium blocks the cholinergic receptors on the bladder wall, it prevents the action of acetylcholine. This relaxes the bladder muscle and helps make the bladder more stable, thus relieving symptoms of bladder instability, such as frequent need to go to the toilet, sudden unexpected urges to go to the toilet, or not making it in time (incontinence).

What is it used for?

- Unstable bladder conditions that cause a frequent need to go the toilet (urinary frequency), needing to suddenly rush to the toilet (urinary urgency) and/or not getting there in time (urge incontinence)

Warning!

- This medicine has not been studied in people with decreased liver function, so is not recommended in this group of people.
- This medicine may cause blurred vision and so may affect your ability to drive or operate machinary safely. Do not drive or operate machinary until you know how this medicine affects you.
- Your doctor should reassess whether you still need treatment with this medicine every three to six months.

Use with caution in

- Coeliac disease
- Congestive heart failure
- Coronary artery disease
- Decreased kidney function
- Disorder of the involuntary nervous system, usually causing weakness and numbness (autonomic neuropathy)
- Hiatus hernia associated with reflux oesophagitis
- Hyperthyroidism
- Narrowing of the outlet of the stomach making it difficult for food to pass into the intestines (pyloric stenosis)
- Obstruction of the stomach or intestines
- Obstruction of the urinary tract (urethra)

Not to be used in

- Abnormal muscle weakness
- Children under 12 years of age
- Closed angle glaucoma
- Difficulty in passing urine (urinary retention)
- Fast, abnormal heart rhythms (tachyarrhythmias)
- Severe inflammation of the bowel and back passage
- Severe kidney failure requiring dialysis
- Sudden expansion of the large intestine seen in advanced ulcerative colitis or Crohn's disease (toxic megacolon)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

- The safety of this medicine in pregnancy has not been established. It should therefore be used with caution during pregnancy, and only if the benefits to the mother outweigh any risks to the foetus. Seek medical advice from your doctor.
- It is not known if this medicine passes into breast milk. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant. Discuss this with your doctor.

Label warnings

- Take this medication an hour before food or on an empty stomach.



The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care or attention by a qualified practitioner. The materials in this web site cannot and should not be used as a basis for diagnosis or choice of treatment. Conditions for use Powered by netdoctor
© Copyright 1998 - 2008 NetDoctor.co.uk - All rights reserved

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