How can this medicine affect other medicines?
There may be an increased risk of drowsiness and sedation if this medicine is taken with alcohol or other medicines that can cause drowsiness, including:
- tricyclic antidepressants, eg amitriptyline
- narcotics, eg morphine, codeine
- benzodiazepines, eg diazepam
- sedating antihistamines, eg chlorpheniramine
- sleeping tablets.
There may be an increase in anticholinergic side effects such as dry mouth and constipation, if this medicine is taken with other medicines that have anticholinergic effects, including:
- antispasmodic medicines, eg hyoscine
- antihistamines, eg meclozine
- anticholinergic medicines for Parkinson's disease, eg procyclidine
- tricyclic antidepressants, eg amitriptyline
- antipsychotic medicines.
The blood levels of phenytoin may be altered by prochlorperazine.
If this medicine is taken with lithium there may be an increased risk of extrapyramidal side effects or severe side effects on the nervous system.
This medicine should be avoided by people taking desferrioxamine.
Prochlorperazine may oppose the effects of levodopa.
Prochlorperazine may enhance the effect of blood pressure lowering medications, causing individuals to feel faint or dizzy.
Other medicines containing the same active ingredients
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