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Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As clotrimazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.
Canesten AF cream is licensed to treat the fungal skin infections athlete's foot (tinea pedis) and jock itch (tinea cruris). The cream should be applied to the affected area(s) of skin thinly two to three times daily and rubbed in gently. Treatment should be continued for at least one month to make sure the infection is fully treated.
If you are using the cream to treat athlete's foot you should make sure you wash and dry the feet, especially between the toes, before applying the cream. You may also want to use Canesten AF powder inside your socks and shoes to help treat the infection and prevent it coming back.
What is it used for?
Warning!
Not to be used in
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
How can this medicine affect other medicines?
This medicine is not known to affect other medicines.
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