Flixotide

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Yeast infection of the mouth (oral thrush)

Throat irritation

Hoarse voice

Unexpected narrowing of the airways (paradoxical bronchospasm)

Systemic effects (eg, Cushing's syndrome, adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, cataract and glaucoma) may occur after taking high doses for prolonged periods - see warning above.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

The following medicines may increase the amount of fluticasone that is found in the bloodstream after inhaling the medicine:

ketoconazole, itraconazole

protease inhibitors for HIV infection, such as ritonavir.

These medicines can therefore increase your exposure to fluticasone and so increase the risk of side effects on the rest of the body. These are called systemic side effects, for example, decreased production of natural steroid hormones by the adrenal glands (adrenal suppression) and Cushing's syndrome.

Due to this risk, Flixotide is not recommended for people who are taking ritonavir.

The antifungals ketoconazole and itraconazole should be used with caution in people using Flixotide. Long courses of treatment with these antifungals should be avoided where possible.

Other medicines containing the same active ingredient

There are currently no other inhaler devices for asthma available in the UK that contain fluticasone as the sole active ingredient.

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