Soltamox

How can this medicine affect other medicines?

You should tell your doctor or pharmacist what medicines you are using, particularly those listed below, before you start treatment with this medicine. This includes those bought without a prescription and herbal medicines. Likewise, check with your doctor or pharmacist before starting any new medicines while you are taking this medicine, so they can check that the combination is safe.

Medicines that contain oestrogens, for example oral contraceptives or HRT, should not be used in combination with this medicine, as they will oppose its action.

There may be an increased risk of abnormal blood clots in the veins (thromboembolism) if tamoxifen is used in combination with cytotoxic chemotherapy medicines. Your doctor may prescribe you a medicine to prevent blood clots if you are having chemotherapy with tamoxifen.

Tamoxifen decreases the removal of the anticoagulant medicines nicoumalone and warfarin from the body and hence increases their anti-blood-clotting effect. Women taking anticoagulants in combination with tamoxifen should have their blood-clotting time (INR) regularly monitored, and your doctor may need to reduce the dose of your anticoagulant.

Other medicines containing the same active ingredient

Nolvadex D

Tamoxifen tablets are also available without a brand name, ie as the generic medicine.

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