Benadryl plus

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

This medicine should not be taken at the same time as, or within two weeks of, taking a type of medicine called a monoamine-oxidase inhibitor (MAOI). This is because if pseudoephedrine is taken with an MAOI it may result in a dangerous rise in blood pressure (hypertensive crisis). MAOIs include the following:

- MAOI antidepressants, eg moclobemide, phenelzine, isocarboxazid, tranylcypromine
- the antibiotics linezolid or furazolidone
- rasagiline for Parkinson's disease.

If pseudoephedrine is taken in combination with any of the following medicines it may cause a rise in blood pressure and these should therefore be avoided while taking this medicine:

- amphetamine-like stimulants
- appetite suppressants
- other decongestants.

Pseudoephedrine may interfere with the blood pressure lowering effect of the following medicines for high blood pressure:

- bethanidine
- bretylium
- debrisoquine
- guanethidine.

Other medicines containing the same active ingredients

There are currently no other medicines available in the UK that contain both acrivastine and pseudoephedrine as the active ingredients.

Benadryl allergy relief contains just acrivastine.

Contac, Galpseud and Sudafed contain just pseudoephedrine.

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