How can this medicine affect other medicines?

High doses of ciclosporin increase the blood levels and risk of side effects of doxorubicin. There may be an increased risk of side effects if this medicine is used with other anticancer medicines. Barbiturates such as phenobarbital may reduce the effects of doxorubicin. Doxorubicin may decrease the effects of stavudine. Some cytotoxic anticancer medicines can reduce the blood levels of some antiepileptic medicines, therefore if doxorubicin is given to people taking antiepileptics, the blood levels of these medicines should be monitored so that seizures can be prevented. Some anticancer medicines can increase the blood-thinning effect of anticoagulants such as warfarin, therefore if doxorubicin is given to people taking warfarin, blood clotting times (INR) should be monitored. The response of the body to immunization is reduced by cytotoxic medicines. Therefore, in people receiving doxorubicin treatment, the effectiveness of vaccines may be poor, and infection may occur in patients who receive live vaccines, such as BCG, MMR, oral polio, rubella or yellow fever vaccines.

Other medicines containing the same active ingredients

Caelyx

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