Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Rash

Abdominal pain

Diarrhoea

Drowsiness

Nausea

Indigestion (dyspepsia)

Ulceration of the stomach or intestine

Bleeding from the stomach

Retention of water in the body tissues (fluid retention), resulting in swelling (oedema)

Dizziness

Blood disorders

Lung disorders

Kidney disease

Visual disturbances

Inflammation of the pancreas (pancreatitis)

Abnormal reaction of the skin to light, usually a rash (photosensitivity)

Severe flaking of the surface layer of the skin (toxic epidermal necrolysis)

Narrowing of the airways (bronchospasm)

Damage to the liver

Severe swelling of lips, face or tongue (angioedema)

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Phenylbutazone may enhance the effect of the following medicines, resulting in an increased risk of side-effects or toxicity: baclofen, cyclosporin, digoxin, lithium, methotrexate, phenytoin, quinolone antibiotics, zidovudine and especially blood-thinning or anti-clotting medicines. Phenylbutazone enhances the effect of antidiabetic tablets (belonging to the sulphonylurea group), leading to low blood sugar levels. The effect of phenylbutazone may be enhanced by the following medicines, resulting in an increased risk of side-effects or toxicity: misoprostol, moclobemide, oxpentifylline, probenecid, ritonavir and steroids. The effect of phenylbutazone may be reduced by colestyramine, resulting in it being less effective. The effect of water tablets (diuretics) and blood pressure lowering agents may be reduced by phenylbutazone, resulting in their being less effective. The use of phenylbutazone with diuretics or ACE inhibitors may increase the risk of kidney problems and/or an altered potassium balance. NSAIDs should not be used within 8-12 days of taking mifepristone. Phenylbutazone should not be taken with another NSAID.

Other medicines containing the same active ingredients

Butacote

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