Nexium

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Headache

Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain

Excess gas in the stomach and intestines (flatulence)

Dry mouth

Skin reactions such as rash and itch

Inflammation of the skin (dermatitis)

Dizziness

Pins and needles (paraesthesia)

Difficulty sleeping (insomnia)

Sleepiness (somnolence)

Swelling of the legs and ankles due to excess fluid retention (peripheral oedema)

Pain in the muscles and joints

Increased sweating

Hair loss

Taste disturbance

Blurred vision

Depression

Agitation

Confusion

Liver or blood disorders

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

This medicine should not be taken by people taking atazanavir for HIV infection. This is because esomeprazole may decrease the amount of atazanavir in the blood and could therefore make it less effective against HIV.

Esomeprazole may increase the blood level of the following medicines:

citalopram

clomipramine

diazepam

imipramine

phenytoin (the manufacturer recommends that people taking phenytoin should have their phenytoin blood level checked after starting or stopping esomeprazole).

Esomeprazole may increase the anti-blood-clotting effect of the anticoagulant medicine warfarin. If you are taking warfarin it is recommended that your blood clotting time (INR) is checked after starting and stopping this medicine.

Esomeprazole may decrease the absorption of the following antifungal medicines from the gut, and thus may make them less effective:

itraconazole

ketoconazole.

Other medicines containing the same active ingredient

There are currently no other medicines available in the UK that contain esomeprazole as the active ingredient.

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