Losec

How can this medicine affect other medicines?

You should tell your doctor or pharmacist what medicines you are taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. This is particularly important if you taking any of the medicines mentioned below, because your doctor may need to monitor your treatment or alter your medicine doses. Similarly, you should check with your doctor or pharmacist before taking any new medicines during treatment with this one, to ensure that the combination is safe.

Omeprazole should not be taken by people taking the anti-HIV medicine atazanavir. This is because omeprazole decreases the blood level of atazanavir and could make it less effective at treating HIV infection.

Omeprazole may increase the blood levels of the following medicines and may therefore increase the risk of their side effects:

- warfarin
- acenocoumarol (nicoumalone)
- phenytoin
- benzodiazepines such as diazepam, triazolam, lorazepam or flurazepam
- digoxin
- cilostazol
- tacrolimus.

Due to its effect on the acidity in the stomach, omeprazole may reduce the absorption of the following antifungal medicines from the stomach, which could make them less effective at treating infection:

- ketoconazole
- itraconazole.

Voriconazole may increase the blood level of omeprazole.

Other medicines containing the same active ingredient

Care heartburn relief	Numark heartburn relief	Unichem heartburn relief
Zanprol

Omeprazole capsules and tablets are also available without a brand name, ie as the generic medicine. NB. Generic omeprazole tablets are different from Losec MUPS tablets in that the entire tablet has a special enteric coating. This means that the tablets must be swallowed whole. They cannot be dispersed in the same way as Losec MUPS tablets for people who have difficulty swallowing.

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