How does it work?

Acemetacin belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Once in the body it is partly converted to another NSAID, indometacin. Both work by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation. Acemetacin is used to relieve pain and inflammation. All the medicines in this group reduce inflammation caused by the body's own immune system and are effective pain killers.

What is it used for?

Inflammatory disease of the joints

Lower back pain

Osteoarthritis

Pain and inflammation following surgery

Warning!

This medicine may cause dizziness. Avoid driving and operating machinery if affected.

It is recommended that you receive regular eye examinations while you taking this medicine, as it can sometimes cause eye problems. Consult your doctor if you experience any disturbances in your vision while taking this medicine.

Take this medicine with or after food.

Individuals receiving long-term treatment with this medicine should be regularly monitored (kidney and liver function tests, blood counts).

There is no experience with the use of this medicine in children.

Use with caution in

Decreased kidney function

Decreased liver function

Elderly people

Epilepsy

Heart failure

History of diseases of the stomach or intestines

Imbalance of water and salt concentrations in the blood (fluid and electrolyte imbalance)

Infection of the blood or body tissues with pus-forming or other pathogenic organisms (sepsis)

Parkinson's disease

Psychotic illness

Not to be used in

Active peptic ulcer

Bleeding from the stomach or intestines

Breastfeeding

History of peptic ulcers

Nasal polyps associated with swelling of the lips, eyes and mouth

People in whom aspirin or other medicines in this class (NSAIDs), cause attacks of asthma, itchy rash (urticaria) or nasal inflammation (rhinitis)

Pregnancy

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

The safety of this medicine in pregnancy has not been established. It should not be taken by women who are pregnant, and women of child-bearing age who take this medicine should use effective contraception. Seek medical advice from your doctor.

There is no information available about the safety of this medicine during breastfeeding. For this reason, the manufacturer states that it should not be used during breastfeeding. Seek medical advice from your doctor.

Label warnings

Take this medication with or after food.

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