How does it work?

Tiabendazole is a medication that is used in the treatment of a number of parasitic worm infections. It works by interfering with proteins in either the worm's intestine or absorptive cells. This leads to the worm not being able to absorb sugars which are essential for its survival. Therefore the energy stores of the worm are depleted, and this leads to it's eventual death within several days. Tiabendazole is the main treatment for infections caused by Strongyloides stercoralis. This parasite lives in the gut and produce larvae which penetrate the gut wall. It is also used as an alternative treatment option in hookworm, whipworm, threadworm and roundworm infections. Tiabendazole is indicated as primary treatment against Strongyloidiasis; Cutaneous larva migrans (creeping eruption); Dracunculiasis (guinea worm); Visceral larva migrans. Tiabendazole is indicated as secondary treatment against Enterobiasis (threadworm) when the infestation is mixed with a primary indication. Tiabendazole can relieve the symptoms and fever of trichinosis during the invasion stage. Mintezol is indicated (a) when specific therapy is unavailable, (b) when other therapy cannot be used or (c) as additive therapy against Necator americanus and Ancylostoma duodenale (hookworm); Trichuriasis (whipworm); Ascariasis (large roundworm).

What is it used for?

Additive therapy against Ascariasis (large roundworm)

Additive therapy against infections with Ancylostoma duodenale (hookworm)

Additive therapy against infections with Necator americanus (hookworm)

Additive therapy against Trichuriasis (whipworm)

Primary treatment against infections with cutaneous larva migrans (creeping eruption)

Primary treatment against infections with Dracunculiasis (guinea worm)

Primary treatment against infections with Strongyloides

Primary treatment against visceral larva migrans

Secondary treatment against Enterobiasis (threadworm)

Warning!

This medicine should not be used for the prevention of this condition, only in the treatment.

Use with caution in

Anaemia

Decreased kidney function

Decreased liver function

Dehydration

Elderly people

Malnutrition

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should not be used during pregnancy as it may be harmful to the unborn baby. Seek medical advice from your doctor.

This medicine should not be used by breastfeeding mothers. Discuss this with your doctor.

Label warnings

Take this medication with or after food.

This medication is to be sucked or chewed.

This medication may cause drowsiness. If affected do not drive or operate machinery.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Rash

Severe swelling of lips, face or tongue (angioedema)

Fever (pyrexia)

Loss of appetite

Headache

Itching (pruritus)

Diarrhoea

Drowsiness

Dizziness

Nausea and vomiting

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

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