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Health and Nutrition > Medicines > M

Methylphenobarbital (discontinued in the UK - June 2001) (Contd)




Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

  • Drowsiness
  • Excitement
  • Confusion
  • Blood disorders
  • Restlessness
  • Balance problems involving the inner ear (vertigo)
  • Irritability
  • Decreased co-ordination
  • Allergic skin reactions
  • Difficulty breathing

    • The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

    How can this medicine affect other medicines?

    Methylphenobarbital blood levels may be increased by: Chloramphenicol Dextropropoxyphene and sodium valproate. Methylphenobarbital blood levels may be decreased by cimetidine. In addition, methylphenobarbital may decrease the absorption of cimetidine from the gut. Methylphenobarbital may decrease the blood levels of: Antibiotics such as chloramphenicol, doxycycline, metronidazole, and rifampicin Anticoagulants such as dicoumarol and warfarin Beta-blocker blood pressure lowering medication such as metoprolol and propranolol Corticosteroids such as prednisolone Digoxin and theophylline. Methylphenobarbital may decrease the effectiveness of: Griseofulvin Oral and depot contraception and pethidine. When methylphenobarbital is taken with phenytoin, the blood levels of both medications may be altered. There may be a large increase in sedation when methylphenobarbital is taken with alcohol. There may be an increase in sedation and difficulty breathing when methylphenobarbital is taken with pethidine.

    Other medicines containing the same active ingredients

    Prominal


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