How does it work?

Nalbuphine hydrochloride belongs to a group of medicines called opioids. Opioids mimic the effects of naturally occurring pain reducing chemicals (endorphins). They combine with the opioid receptors in the brain and block the transmission of pain signals. Therefore, even though the cause of the pain may remain, less pain is actually felt. Opioids are commonly used to relieve the pain of heart attack, injury, surgery and terminal diseases.

What is it used for?

Moderate to severe pain

Warning!

This medicine may cause drowsiness. If affected do not drive or operate machinery.

Use with caution in

A dark bluish or purplish coloration of the skin and mucous membrane due to deficient oxygenation of the blood (cyanosis)

Addiction (dependency)

Asthma

Decreased liver function

Head injury

High blood urea levels (uraemia)

Hypothyroidism

Increased pressure in the brain (raised intracranial pressure)

Slow, shallow breathing (respiratory depression)

Not to be used in

Known sensitivity or allergy to any ingredient

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than the possible risk to the foetus. Seek medical advice from your doctor.

The safety of this medicine during breastfeeding has not been established. Seek medical advice from your doctor.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Headache

Dry mouth

Changes in mood

Slow, shallow breathing (respiratory depression)

Sweating

Addiction to the medicine (dependence)

Skin rashes

Low blood pressure (hypotension)

Balance problems involving the inner ear (vertigo)

Dizziness

Nausea and vomiting

Constipation

Drowsiness

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

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