Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Headache

Dry mouth

Disturbed sleep

Anxiety and restlessness

Agitation

Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain

Visual disturbances

Pins and needles (paraesthesia)

Dizziness

Excessive fluid retention in the body tissues, resulting in swelling (oedema)

Skin reactions such as rash and itch

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Moclobemide should not be taken at the same time as monoamine oxidase inhibitor antidepressants (MAOIs), tricyclic antidepressants (TCAs) or selective serotonin re-uptake inhibitor antidepressants (SSRIs). Moclobemide should not be started until approximately two weeks (depending on the antidepressant) after these antidepressants have been stopped. Pethidine and selegiline must not be taken at the same time as moclobemide. Dextromethorphan (which is found in many cough medicines) should not be taken at the same time as moclobemide, as this combination may cause severe adverse effects. The following can cause a dangerous increase in blood pressure when taken in combination with moclobemide, and they should be avoided by people taking this medicine: - ephedrine and other amines that constrict blood vessels, eg pseudoephedrine or phenylpropanolamine (note: cough, cold and flu remedies often contain these ingredients) - amphetamines - ecstasy (MDMA). Moclobemide blood levels may be increased by cimetidine. Your doctor may need to decrease your moclobemide dose if you start taking cimetidine. There may be a dangerous increase in blood pressure if moclobemide is taken with large amounts of tyramine rich foods. Examples of foods to avoid are: - matured cheeses - yeast extracts, eg Oxo, Bovril, Marmite - fermented soya bean products.

Other medicines containing the same active ingredients

Manerix

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