How can this medicine affect other medicines?

Lisinopril may enhance the effect of other medicines that decrease blood pressure (antihypertensives). There may be a large drop in blood pressure with the first dose, particularly in people taking diuretic medicines, eg frusemide. This may cause dizziness or fainting, and for this reason, if you are taking a diuretic medicine, your doctor may reduce the dose or ask you to stop taking it two to three days before starting lisinopril. This is to prevent your blood pressure from dropping too low. There may also be a drop in blood pressure causing dizziness or fainting if lisinopril is taken with the following medicines: - narcotics, eg morphine - antipsychotics, eg chlorpromazine. Non-steroidal anti-inflammatory drugs (NSAIDs, eg indometacin) may reduce the blood pressure lowering effect of lisinopril, and may increase the risk of a decline in kidney function. Lisinopril may increase the blood levels of lithium, and people taking lithium at the same time as lisinopril should have their lithium levels closely monitored. There may be a risk of raised blood potassium levels (hyperkalaemia) if lisinopril is taken with any of the following: - potassium-sparing diuretics (eg spironolactone, triamterene, amiloride) - potassium supplements - potassium-containing salt substitutes - ciclosporin. Lisinopril may enhance the blood sugar lowering effect of insulin and oral antidiabetic medicines, with a risk of hypoglycaemia. People with diabetes should therefore carefully monitor their blood sugar while taking this medicine, particularly in the first few weeks of treatment.

Other medicines containing the same active ingredients

Carace

Zestril

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