Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Allergy to active ingredients (hypersensitivity)

Blood disorders

Red colouration of urine

Pain in the muscles (myalgia)

Joint pain (arthralgia)

Yellowing of the skin and eyes (jaundice)

Alteration in results of liver function tests

Rash (allergic reaction)

Nausea and vomiting

Discolouration of tears and sweat

Inflammation of the front parts of the eye (uveitis)

Difficulty in breathing (dyspnoea)

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Rifabutin decreases the concentration of the following medications in the blood: -Disopyramide, mexiletine, propafenone, quinidine (anti-arrhythmics) -Dapsone -Nicoumalone and warfarin (blood-thinning medications) -Chlorpropamide and tolbutamide (and possibly other sulphonylurea antidiabetic drugs) -Phenytoin and carbamazepine (antiepileptics) -Indinavir and saquinavir (antivirals) -Corticosteroids -Cyclosporin -Oral contraceptives Rifabutin levels in the blood are increased by the following: -Clarithromycin (and possibly other macrolide antibacterials). A reduced dose of rifabutin should be used. -Fluconazole and possibly other triazole antifungals. A reduced dose of rifabutin should be used. -Indinavir, nelfinavir, ritonavir (antivirals) Rifabutin may cause transplant rejection when given with azathioprine.

Other medicines containing the same active ingredients

Mycobutin

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