How does it work?

Acebutolol belongs to a group of medicines called beta-blockers, which block beta receptors in the heart, lungs and other organs of the body. Blocking these receptors prevents the action of two chemicals called noradrenaline and adrenaline that occur naturally in the body. These are often referred to as the 'fight or flight' chemicals as they are responsible for the body's reaction to stressful situations. Blocking the beta receptors in the heart causes the heart to beat more slowly and with less force. The heart therefore uses less energy and the pain of angina is prevented. Abnormal heart rhythms are also prevented. Due to the heart beating more slowly and with less force, the pressure at which blood is pumped out of the heart to the rest of the body is reduced. This is just one of the ways in which beta blockers help to reduce blood pressure, however the whole mechanism is not fully understood.

What is it used for?

Angina pectoris

Fast, abnormal heart rhythms (tachyarrhythmias)

High blood pressure

Warning!

This medicine may mask the symptoms of low blood sugar such as increased heart rate, tremor and nausea. People with diabetes should carefully monitor their blood sugar.

You should not suddenly stop taking this medicine unless your doctor tells you otherwise.

This medicine may mask the symptoms of the condition caused by an excess of thyroid hormone (thyrotoxicosis).

The dose of this medicine for use in children has not been established.

Use with caution in

Chronic obstructive pulmonary disease

Diabetes

History of asthma or wheezing

Low blood pressure (hypotension)

Severely decreased kidney function

Not to be used in

Allergy to beta-blockers

Defect of the heart's electrical message pathways resulting in decreased function of the heart (heart block)

Failure of the heart to maintain adequate circulation (cardiogenic shock)

Uncontrolled heart failure

Very slow heart rate (severe bradycardia)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine is not recommended for use in pregnancy, particularly in the first and third trimesters, unless considered essential by your doctor. Seek medical advice from your doctor.

This medicine passes into breast milk. Breastfeeding is not recommended when taking this medicine. Seek medical advice from your doctor.

Label warnings

Do not stop taking this medication except on your doctor's advice.

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