How can this medicine affect other medicines?

Phenytoin blood levels may be increased by: Amiodarone Antibiotics such as chloramphenicol, isoniazid and sulphonamides (e.g. co-trimoxazole) Anti-epileptic succinimides such as ethosuximide Anti-fungals such as fluconazole and miconazole Benzodiazepines such as chlordiazepoxide and diazepam Dicoumarol Disulfiram Methylphenidate Phenothiazines such as chlorpromazine Phenylbutazone Ulcer-healing medicines such as cimetidine and omeprazole and viloxazine. Phenytoin blood levels may be decreased by: Carbamazepine Chronic heavy alcohol consumption Folic acid Sucralfate and vigabatrin. Phenytoin blood levels may be changed by: Anti-cancer medicines Ciprofloxacin Phenobarbitone (phenobarbital) and sodium valproate or valproic acid. Phenytoin may change the blood levels of: Phenobarbitone (phenobarbital) and sodium valproate or valproic acid. Phenytoin may decrease the effectiveness of: Anti-cancer medicines Anti-fungals such as ketoconazole Clozapine Corticosteroids such as prednisolone Dicoumarol Digoxin Doxycycline Frusemide (furosemide) Oral contraceptives Quinidine Theophylline and vitamin D. Phenytoin may increase the anti-clotting effect of warfarin. The risk of seizures occurring may be increased by tricyclic antidepressants such as amitriptyline and possibly phenothiazines such chlorpromazine. Phenytoin doses may need to changed to decrease this risk.

Other medicines containing the same active ingredients

Epanutin Capsules

Epanutin Infatabs

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