Temgesic injection

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Nausea and vomiting

Dizziness

Drowsiness

Sweating

Headache

Skin rashes

Blurred vision

Difficulty in passing urine (urinary retention)

Low blood pressure (hypotension)

False perceptions of things that are not really there (hallucinations)

Slow, shallow breathing (respiratory depression)

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

There may be an increased risk of side effects such as drowsiness, sedation, low blood pressure and slow, shallow breathing, if this medicine is used with other medicines that have a sedative effect on the central nervous system. These include the following:

alcohol

antipsychotics, eg haloperidol

barbiturates, eg phenobarbital, amobarbital

benzodiazepines, eg diazepam, temazepam

other opioid painkillers, eg codeine, morphine

sedating antihistamines, eg chlorphenamine, hydroxyzine

sleeping tablets, eg zopiclone

tricyclic antidepressants, eg amitriptyline.

The antifungal medicine ketoconazole increases the blood level of this medicine. Your dose of buprenorphine should be reduced if you start treatment with ketoconazole.

In people who are highly dependent on other opioids, eg morphine, diamorphine, methadone, this medicine may cause some withdrawal symptoms. This is because buprenorphine can block some of the effects of other opioids.

The manufacturer states that this medicine should be used with caution in people who are taking a type of medicine called a monoamine oxidase inhibitor (MAOI), for example, the antidepressants isocarboxazid, phenelzine or tranylcypromine.

Other medicines containing the same active ingredient

BuTrans

Temgesic sublingual tablets

Transtec

Subutex also contains buprenorphine, but is used to treat opioid dependence and is not for pain relief.

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