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Solpadol

Health and Nutrition > Medicines > S

Solpadol (Contd)




Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

  • Constipation
  • Nausea and vomiting
  • Dizziness
  • Lightheadedness
  • Drowsiness
  • Shortness of breath
  • Confusion
  • Mood changes
  • Difficulty in passing urine (urinary retention)
  • Skin rash
  • Dry mouth
  • Slowed heart rate
  • Contraction of the pupils
  • The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

    How can this medicine affect other medicines?

    It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

    You should not take other medicines that contain paracetamol in combination with this medicine, as this can easily result in exceeding the maximum recommended daily dose of paracetamol. Many cold and flu remedies and over-the-counter painkillers contain paracetamol, so be sure to check the ingredients of any other medicines before taking them with this one.

    This medicine should not be taken at the same time as, or within 14 days of taking a monoamine oxidase inhibitor (MAOI), for example the antidepressants phenelzine, tranylcypromine or isocarboxacid.

    There may be an increased risk of drowsiness and sedation if this medicine is taken with any of the following (which can also cause drowsiness):

  • alcohol
  • antipsychotics, eg haloperidol
  • barbiturates, eg phenobarbital, amobarbital
  • benzodiazepines, eg diazepam, temazepam
  • other opioid painkillers, eg morphine, dihydrocodeine
  • sedating antihistamines, eg chlorphenamine, hydroxyzine
  • sleeping tablets, eg zopiclone
  • tricyclic antidepressants, eg amitriptyline.
  • Cholestyramine reduces the absorption of paracetamol from the gut. It should not be taken within an hour of taking paracetamol or the effect of the paracetamol will be reduced.

    Metoclopramide and domperidone may increase the absorption of paracetamol from the gut.

    Long-term or regular use of paracetamol may increase the anti-blood-clotting effect of warfarin and other anticoagulant medicines, leading to an increased risk of bleeding. This effect does not occur with occasional pain-killing doses. If you are taking an anticoagulant medicine and you are also taking co-codamol regularly, your blood clotting time (INR) should be regularly monitored.

    Other medicines containing the same active ingredients

    Prescription only brands:

    Codipar Kapake Medocodene
    Tylex Zapain
    Non-prescription brands:

    Feminax Migraleve yellow Panadol ultra
    Paracodol Solpadeine Max
    Co-codamol tablets, effervescent tablets and capsules are also available without a brand name (ie as the generic medicine) in both prescription and non-prescription strengths.



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