How does it work?

The exact mechanism by which cyclizine prevents nausea and vomiting is not fully understood, however, various actions are established. Cyclizine belongs to a group of medicines called antihistamines. These medicines block histamine receptors which are found in various places in the body, including an area in the brain known as the vomiting centre. This area controls vomiting. Cyclizine blocks histamine receptors in the vomiting centre, the result of which is to prevent the brain from sending the nerve messages to the stomach that would normally result in the action of vomiting. Cyclizine also tightens the muscles at the entrance to the stomach which physically helps to prevent vomiting. Furthermore, it reduces the sensitivity of the inner ear, which is one way in which cyclizine can control the symptoms of vertigo, however this is not fully understood.

What is it used for?

Balance problems involving the inner ear (vertigo)

Motion sickness

Nausea and vomiting

Warning!

Do not drink alcohol whilst taking this medicine.

Use with caution in

Enlarged prostate gland

Glaucoma

Obstruction of the gut

Severe heart failure

Not to be used in

Allergy to any of the active ingredients

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

The safety of this medicine during pregnancy has not been established. The manufacturer therefore advises that it should be avoided during pregnancy. Seek medical advice from your doctor.

There is no information available regarding the safety of this medicine during breastfeeding. Seek medical advice from your doctor.

Label warnings

This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

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