How does it work?

Promethazine theoclate belongs to a group of medicines called antihistamines. These medicines block histamine receptors which are found in various places in the body, including an area in the brain known as the vomiting centre. This area controls vomiting. Promethazine blocks histamine receptors in the vomiting centre, thereby preventing nausea and vomiting. Promethazine is also used to treat vertigo, however it is not fully understood how it works in this condition.

What is it used for?

Balance problems involving the inner ear (vertigo)

Motion sickness

Nausea and vomiting

Warning!

This medicine may reduce your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance.

This medicine may interfere with some pregnancy tests, causing false negative or false positive results.

This medicine should be discontinued at least 72 hours before allergy skin tests, as it may cause false negative results.

Use with caution in

Asthma

Breastfeeding

Bronchitis

Closed angle glaucoma

Decreased kidney function

Epilepsy

Liver disease

Obstruction of the bladder or intestine

Pregnancy

Severe coronary artery disease

Widening of the airways which may be hereditary or due to infection (bronchiectasis)

Not to be used in

Allergy to phenothiazines such as chlorpromazine and prochlorperazine

Babies less than one month old (neonates)

People who have taken monoamine-oxidase inhibitor antidepressants (MAOIs) in the last 14 days

Premature infants

Reduced awareness, slow reactions or drowsiness due to medicines or illness that reduce activity in the central nervous system

Unresponsive unconscious states (comatose states)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than the possible risk to the foetus. Seek medical advice from your doctor.

This medicine should be used with caution by breastfeeding mothers, and only if the expected benefit to the mother is greater than the possible risk to the baby. Seek medical advice from your doctor.

Label warnings

This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

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