Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Headache
Rash
Blurred vision
A drop in blood pressure that occurs when going from lying down to sitting or standing, which results in dizziness and lightheadedness (postural hypotension)
Fatigue
Agitation
Weight gain
High blood glucose level (hyperglycaemia)
Problems with sexual function
Dizziness
Abnormal movements of the hands, legs, face, neck and tongue, eg tremor, twitching, rigidity (extrapyramidal effects)
Excessive fluid retention in the body tissues, resulting in swelling (oedema)
Sleepiness (somnolence)
Inflammation of the lining of the nose (rhinitis) causing a blocked or runny nose
Anxiety
High blood prolactin (milk producing hormone) level (hyperprolactinaemia). Rarely this may lead to symptoms such as breast enlargement, production of milk and menstrual disturbances.
Disturbances of the gut such as constipation, nausea, vomiting or abdominal pain
Difficulty in sleeping (insomnia)
Concentration difficulties
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines?
There may be an increased risk of drowsiness and sedation if risperidone is taken with any of the following (which can also cause drowsiness):
- alcohol
- tricyclic antidepressants, eg amitriptyline
- narcotics, eg morphine, codeine
- benzodiazepines, eg diazepam
- sedating antihistamines, eg chlorpheniramine
- sleeping tablets.
There may be an increased risk of abnormal heart rhythms (prolonged QT interval on the heart monitoring trace or ECG) if risperidone is taken with any of the following medicines:
- antiarrhythmics, eg amiodarone, procainamide, disopyramide, sotalol
- antidepressants, eg amitriptyline, imipramine, maprotiline
- the anthistamines astemizole (no longer available in the UK) or terfenadine
- antimalarials, eg halofantrine, chloroquine, quinine
- antipsychotics, eg thioridazine, chlorpromazine, sertindole, haloperidol
- intravenous erythromycin or pentamidine
- cisapride.
Risperidone may oppose the effects of levodopa and dopamine agonists used to treat Parkinson's disease.
Carbamazepine may reduce the blood level of risperidone.
Fluoxetine may increase the blood level of risperidone.
Other medicines containing the same active ingredients
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