Zyloric

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Allergic skin reactions such as rash or itch

Sleepiness

Balance problems involving the inner ear (vertigo)

Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain

Fever (pyrexia)

A general feeling of being unwell (malaise)

Headache

Weakness, numbness or pins and needles

Visual disturbances

Alteration in taste

Chest pain (angina)

Loss or discolouration of hair

High blood pressure (hypertension)

Enlargement of the breasts

Impotence or infertility

Liver disorders

Blood disorders

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

Allopurinol increases the effects of azathioprine and mercaptopurine. A lower than normal dose of these medicines is necessary if they are taken with allopurinol.

Allopurinol may slow down the removal of the chemotherapy medicine vidarabine from the body and so may increase the risk of it's side effects.

Allopurinol may enhance the effects of anti-blood-clotting medicines (anticoagulants) such as warfarin in some people. For this reason all people taking anticoagulants such as warfarin should have their blood clotting time monitored when starting treatment with allopurinol.

Allopurinol may increase the blood level of theophylline. If you are taking theophylline your doctor may want to monitor your theophylline blood level if you start treatment with allopurinol or your dose is increased.

Allopurinol may increase the blood level of ciclosporin.

There is an increased chance of a skin rash if the antibiotics amoxicillin or ampicillin are taken by people taking allopurinol.

Other medicines containing the same active ingredient

Allopurinol tablets are also available as the generic medicine, ie without a brand name.

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