Health Centres - Zinnat (cefuroxime)
How does it work?
Zinnat tablets and suspension contain the active ingredient cefuroxime, which is a type of medicine called an antibiotic. (NB. Cefuroxime is also available without a brand name, ie as the generic medicine.) Cefuroxime is a type of antibiotic called a cephalosporin. These antibiotics are related to penicillin. Cefuroxime is used to treat infections caused by bacteria.
Cefuroxime works by interfering with the ability of bacteria to form cell walls. The cell walls of bacteria are vital for their survival. They keep unwanted substances from entering their cells and stop the contents of their cells from leaking out. Cefuroxime impairs the bonds that hold the bacterial cell wall together. This allows holes to appear in the cell walls and kills the bacteria.
Cefuroxime is a broad-spectrum antibiotic that kills a wide variety of bacteria that cause a wide variety of commonly occuring infections. Cefuroxime is given by mouth to treat infections of the upper and lower airways, ears, nose and throat, and skin and soft tissue. It may also be used to treat urinary tract infections, certain sexually-transmitted infections, and Lyme disease.
To make sure the bacteria causing an infection are susceptible to cefuroxime your doctor may take a tissue sample, for example a swab from the throat or skin, or a urine or blood sample.
What is it used for?
- Bacterial infections of the lungs (chest or lower respiratory tract), eg acute bronchitis, pneumonia
- Bacterial infection of the nasal passages, sinuses or throat (upper respiratory tract infection), eg sinusitis, pharyngitis, laryngitis, tonsillitis
- Bacterial infections of the ear, eg otitis media
- Bacterial infections of the urinary tract, eg cystitis, inflammation of the urethra due to infection (urethritis), kidney infections (pyelonephritis)
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Gonorrhoea
- Inflammation of the cervix due to bacterial infection (cervicitis)
- Bacterial infections of the skin or soft tissue, eg boils, abscesses, impetigo
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Lyme disease.
Warning!
- Unless your doctor tells you otherwise, it is important that you finish the prescribed course of this antibiotic medicine, even if you feel better or it seems the infection has cleared up. Stopping the course early increases the chance that the infection will come back and that the bacteria will grow resistant to the antibiotic.
- Broad-spectrum antibiotics can sometimes cause inflammation of the bowel (colitis). For this reason, if you get diarrhoea that becomes severe or persistent or contains blood or mucus, either during or after taking this medicine, you should consult your doctor immediately.

