Vibramycin

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

- Blood disorders
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Loss of appetite
- Disturbances of liver function
- Inflammation of the food pipe (oesophagitis)
- Difficulty or pain when swallowing (dysphagia)
- Inflammation of the intestines (enterocolitis)
- Mild increase in pressure within the skull (benign intracranial hypertension)
- Hypersensitivity reactions such as swelling of the lips, throat and tongue (angioedema), itchy blistering rash or anaphylactic shock
- Rash
- Diarrhoea
- Nausea and vomiting

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

The absorption of doxycycline from the gut may be reduced by the following: - antacids containing aluminium, magnesium, calcium or bismuth salts (the dose of antacids should be separated from the doxycycline dose by at least two to three hours if they must be used) - iron preparations - zinc salts. In addition, doxycycline reduces the absorption of iron preparations taken by mouth. Doxycycline may reduce the effectiveness of the combined oral contraceptive pill. Doxycycline may increase the anti-blood-clotting effects of anticoagulants such as warfarin. People taking this type of medicine should be monitored when doxycycline is first added to treatment. The following medicines may reduce the blood level of doxycycline: - barbiturates, eg phenobarbitone - carbamazepine - phenytoin. Your doctor may need to increase the dose of doxycycline if you are taking these medicines. Tetracyclines in general may decrease the effectiveness of penicillin type antibiotics. This medicine should be avoided with penicillin. Alcoholics may have reduced blood levels of doxycycline. This is because in this group of people alcohol stimulates the liver to metabolise the doxycycline. Alcohol has not been found to have this effect in people who drink moderately.

Other medicines containing the same active ingredients

Doxycycline

Doxylar

Vibramycin-D

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