Transiderm-Nitro patches (glyceryl trinitrate)

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

- Headache.
- Dizziness.
- Weakness.
- Nausea.
- Flushing.
- Reddening, itching or burning sensation at the patch application site.
- A drop in blood pressure that occurs when moving from a lying down or sitting position to sitting or standing, which results in dizziness and lightheadedness (postural hypotension).
- Increased heart rate (tachycardia).
- Decreased heart rate (bradycardia).
- Allergic skin reactions.
- Fainting.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while using this one, to ensure that the combination is safe.

The medicines for erectile dysfunction (impotence) listed below must not be used by people using glyceryl trinitrate, because the combination can produce a severe drop in blood pressure resulting in dizziness, fainting, or even a heart attack:

- sildenafil (Viagra)
- tadalafil (Cialis)
- vardenafil (Levitra).

If this medicine is used in combination with other medicines that reduce blood pressure, either as a treatment for high blood pressure (antihypertensives), or as a side effect, there may be an enhanced blood pressure lowering effect. This might make some people feel dizzy. If you do feel dizzy, you should lie down until the symptoms pass. Other medicines that can reduce blood pressure include the following:

- ACE inhibitors, eg enalapril, captopril
- alpha blockers, eg alfuzosin, doxazosin
- alprostadil
- anaesthetics
- angiotensin II receptor antagonists, eg losartan
- certain antipsychotic medicines, eg chlorpromazine
- baclofen
- benzodiazepines, eg temazepam
- beta-blockers, eg propranolol
- calcium channel blockers, eg diltiazem, verapamil, nifedipine
- clonidine
- diuretics, eg furosemide
- hydralazine
- levodopa
- MAOI antidepressants, eg phenelzine
- methyldopa
- minoxidil
- moxisylyte
- moxonidine
- other nitrates, eg isosorbide mononitrate, amyl nitrate (poppers)
- tricyclic antidepressants, eg amitriptyline.

Other medicines containing the same active ingredient

Coro-Nitro pump spray	Deponit patches	Glytrin spray
GTN sublingual tablets	Minitran patches	Nitrocine injection
Nitro-Dur patches	Nitrolingual pump spray	Nitromin spray
Percutol ointment	Suscard tablets

Glyceryl trinitrate sublingual tablets, sprays and injection are also available without a brand name, ie as the generic medicine.

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