Health Centres - Topicycline (discontinued in the UK - January 2007)
How does it work?
Tetracycline is a type of antibiotic that has activity against a wide variety of bacteria, including the bacteria associated with acne, Propionebacterium acnes. This is a common type of bacteria that feeds on sebum produced by the sebaceous glands in the skin. It produces waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots.
What is it used for?
Warning!
- This preparation is for external use only.
- Avoid contact of this medicine with the eyes and the moist membranes lining the inside of certain parts of the body, eg mouth, nasal passages (mucous membranes). Rinse with cold water if accidental contact occurs.
- This medicine may leave a yellow colour on the skin it is applied to, which may stain clothing or bed linen. You can avoid staining of fabrics by lightly washing the affected skin one hour after applying the solution.
- There may be an abnormal reaction of the skin to sunlight (photosensitivity, eg a rash) while using this medicine. Avoid exposing the affected area(s) of skin to sunlight, particularly if you have fair skin.
Use with caution in
- Decreased kidney function
Not to be used in
- Allergy to other tetracycline antibiotics, eg doxycycline, minocycline
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- It is not known if this medicine passes into breast milk. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant. Discuss this with your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
- Skin rashes
- Stinging or tingling of the skin at the site of application
- Skin discolouration at application site
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
