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Penicillins such as ticarcillin may decrease the removal of methotrexate from the body, increasing the risk of its side effects. Your doctor may want to monitor the amount of methotrexate in your blood if you are receiving methotrexate treatment in combination with this medicine.
Ticarcillin may rarely alter the anti-blood-clotting effects of anticoagulant medicines such as warfarin. Your doctor may want to monitor your blood clotting time more frequently if you are taking an anticoagulant in combination with this medicine.
Probenecid is not recommended in combination with this medicine.
If you are taking a combined oral contraceptive pill or are using contraceptive patches, there may be a very low risk that this antibiotic may make it less effective at preventing pregnancy. Although the risk of this is very low, the personal and ethical consequences of an unwanted pregnancy can be very serious. For this reason, the Family Planning Association recommends that women using a combined contraceptive pill or patch should use an extra method of contraception (eg condoms) while having treatment with a short course of broad-spectrum antibiotic, and for seven days after finishing the course. If the seven days run beyond the end of a pill packet, a new packet should be started without a break (in the case of ED pills the inactive tablets should be omitted). If the seven days run beyond the 3 weeks of patch treatment, a new treatment cycle should be started immediately without a patch-free break.
Other medicines containing the same active ingredients
There are currently no other medicines available in the UK that contain ticarcillin and clavulanic acid as the active ingredients.
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