Surgam SA (discontinued in the UK- January 2007)

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

- Abdominal pain
- Diarrhoea
- Nausea
- Indigestion (dyspepsia)
- Ulceration of the stomach or intestine
- Bleeding from the stomach
- Rash (allergic reaction)
- Retention of water in the body tissues (fluid retention)
- Blood disorders
- Inflammation of the pancreas (pancreatitis)
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Severe flaking of the surface layer of the skin (toxic epidermal necrolysis)
- Narrowing of the airways (bronchospasm)
- Severe swelling of lips, face or tongue (angioedema)

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Tiaprofenic acid may enhance the effect of the following medicines, resulting in an increased risk of side-effects or toxicity: cyclosporin, digoxin, lithium, methotrexate, quinolone antibiotics, zidovudine and blood-thinning or anti-clotting medicines. Tiaprofenic acid may also enhance the effect of antidiabetic tablets (belonging to the sulphonylurea group), which could lead to low blood sugar levels. The effect of tiaprofenic acid may be enhanced by ritonavir resulting in an increased risk of side-effects or toxicity. The effect of water tablets (diuretics) and blood pressure lowering agents may be reduced by tiaprofenic acid resulting in their being less effective. Use of tiaprofenic acid with diuretics or ACE inhibitors may increase the risk of kidney problems and/or an altered potassium balance. NSAIDs should not be taken fpr 8-12 days after taking mifepristone. Tiaprofenic acid should not be taken with any other NSAID.

Other medicines containing the same active ingredient

Surgam

Tiaprofenic acid is also available without a brand name, ie as the generic medicine.

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