Stugeron (cinnarizine)

How does it work?

Stugeron tablets contain the active ingredient cinnarizine, which is a type of medicine called an antihistamine. (NB. Cinnarizine is also available without a brand name, ie as the generic medicine.) Cinnarizine is used to control travel sickness and the symptoms of inner ear disorders such as Meniere's disease.

Vomiting is controlled by an area of the brain called the vomiting centre. The vomiting centre is responsible for causing feelings of sickness (nausea) and for the vomiting reflex. It is activated when it receives nerve messages from the vestibular apparatus in the middle ear.

The vestibular apparatus provides continual feedback to the brain about our body position. When something disturbs the vestibular apparatus, such movement of the head when travelling by boat or car, nerve signals are sent from the vestibular apparatus to the vomiting centre. This can cause sensations such as nausea, dizziness or spinning sensations (vertigo) and the reflex of vomiting.

Cinnarizine works by blocking histamine and muscarinic receptors in the vomiting centre in the brain. This prevents the vomiting centre from receiving nerve messages from the vestibular apparatus. In turn, this prevents disturbances in the middle ear from activating the vomiting centre and causing nausea, vertigo and vomiting.

What is it used for?

Preventing and treating motion sickness

Relieving nausea, vomiting, attacks of dizziness or spinning sensations (vertigo) and sensations of ringing or other noise in the ears (tinnitus) associated with Meniere's disease and other middle ear disorders.

Warning!

This medicine may cause drowsiness. If affected do not drive or operate machinery. Alcohol should be avoided.

If you find this medicine upsets your stomach, taking it with or after food may help.

If you are due to have any skin prick tests to diagnose allergies you should stop taking this medicine at least 48 hours before the tests. This is because antihistamines can prevent or lessen the skin reactions that indicate an allergy, and so can make the test results unreliable.

Use with caution in

Decreased kidney function

Decreased liver function

Parkinson's disease.

Not to be used in

Children under five years of age

Hereditary blood disorders called porphyrias

Pregnancy

Breastfeeding

Rare hereditary problems of fructose or galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption or sucrase-isomaltase insufficiency (Stugeron tablets contain lactose and sucrose).

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

The safety of this medicine when used during pregnancy has not been established. It is not recommended for use by pregnant women. Seek medical advice from your doctor.

It is not known if this medicine passes into breast milk. It is not recommended for mothers who are breastfeeding. Consult your doctor for further advice.

Label warnings

This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

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