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The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you take this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
You should not take other medicines that contain paracetamol in combination with this medicine, as this can easily result in exceeding the maximum recommended daily dose of paracetamol. Many cold and flu remedies and over-the-counter painkillers contain paracetamol, so be sure to check the ingredients of any other medicines before taking them with this one.
There may be an increased risk of drowsiness and sedation if this medicine is taken with any of the following (which can also cause drowsiness):
This medicine should be used with caution in people taking a monoamine oxidase inhibitor antidepressant (MAOI), for example phenelzine, tranylcypromine or isocarboxazid. Ask your doctor or pharmacist for advice if you are taking one of these medicines.
Cholestyramine reduces the absorption of paracetamol from the gut. It should not be taken within an hour of taking this medicine or the effect of the paracetamol will be reduced.
Metoclopramide and domperidone may increase the absorption of paracetamol from the gut.
Long-term or regular use of paracetamol may increase the anti-blood-clotting effect of warfarin and other anticoagulant medicines, leading to an increased risk of bleeding. This effect does not occur with occasional pain-killing doses. If you are taking an anticoagulant medicine and you are also taking this medicine regularly, your blood clotting time (INR) should be regularly monitored.
Other medicines containing the same active ingredients
| Co-dydramol | Paramol | Remedeine forte |