Health Centres - Provigil
How does it work?
Provigil tablets contain the active ingredient modafinil, which is a type of medicine known as a CNS stimulant. It works by stimulating activity within the central nervous system, ie brain and spinal cord.
Modafinil increases wakefulness and daytime alertness in people who experience excessive sleepiness during the day, either due to narcolepsy, or due to a syndrome called obstructive sleep apnoea. It can also be used to improve wakefulness and alertness in people who suffer moderate to severe sleep disorders as a result of chronic shift work. However, the medicine should not be used as a replacement for sleep and you should talk to your doctor about ways to try and maintain good sleep patterns.
The way in which modafinil improves wakefulness is not yet fully understood, but it is believed to have an effect on specific parts of the brain responsible for keeping us awake.
Modafinil's mode of action appears to be different to other CNS stimulants, such as the amphetamine group of medicines that are also sometimes used to promote wakefulness. This difference is believed to reduce modafinil's potential for abuse and dependence, though there may still be a risk of this if the medicine is used long-term.
What is it used for?
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Excessive daytime sleepiness due to obstructive sleep apnoea/hypopnoea syndrome
- Excessive daytime sleepiness due to the sleep disorder narcolepsy
- Excessive sleepiness due to moderate to severe sleep disorders associated with chronic shift work
Warning!
- This medicine may cause dizziness and blurred vision. If affected, caution is required when driving or operating machinery.
- The safety of this medicine during pregnancy has not been established. Because it may be harmful to a developing baby, women who could get pregnant should use a reliable contraceptive method to prevent pregnancy while using this medicine. Contraception should be continued for two months after stopping treatment. There is more information about the effect of this medicine on contraceptive pills and patches at the end of this factsheet. It is important to discuss contraceptive methods with your doctor before you start taking this medicine.
- Dependence on this medicine may occur if it used for long periods of time.
- There is insufficient information regarding the safety and efficacy of this medicine in children. It is not recommended for children.
Use with caution in
- Elderly people
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Heart disease
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High blood pressure (blood pressure and heart rate should be monitored)
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Kidney failure
- Liver failure
- Severe anxiety
Not to be used in
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