Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Rash

Slower than normal heart beat (bradycardia)

Changes in mood

Fatigue

Nightmares

Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain

Blockade of the electrical pathways which control the pumping action of the heart (heart block)

Cold extremities, eg hands and feet

Dizziness

Breathing difficulties due to a narrowing of the airways (bronchospasm)

A drop in blood pressure that occurs when going from lying down to sitting or standing, which results in dizziness and lightheadedness (postural hypotension)

Hair loss (alopecia)

Worsening of the skin condition psoriasis

Decrease in the number of platelets in the blood (thrombocytopenia)

Deterioration of heart failure

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

In diabetic patients, propranolol can prolong the lowering of blood sugar (hypoglycaemia) caused by insulin or other antidiabetic medicines. Individuals should monitor their blood sugar, as propranolol can also mask the signs of hypoglycaemia. When propranolol is taken together with calcium channel blockers such as verapamil, nifedipine or diltiazem, the risk of slow heart rate, hypotension and heart failure may be increased. Neither propranolol nor calcium channel blockers should be given intravenously within 48 hours of discontinuing the other. If propranolol is taken together with clonidine, there is a risk of a rebound increase in blood pressure if clonidine is stopped. The propranolol should be stopped several days before slowly stopping the clonidine. Non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin may reduce the antihypertensive effects of propranolol. Care should be taken when adrenaline is given with propranolol as this combination can cause severely high blood pressure and slow heart rate. Anti-arrhythmic medicines such as amiodarone or disopyramide may increase the risk of slow heart rate when taken with this medicine. There is an increased risk of slow heart rate when propranolol is taken with digoxin. When taken with ergotamine or dihydroergotamine there may be an increased risk of adverse reactions involving the blood circulation to the extremities. Administration of propranolol during an intravenous infusion of lidocaine (lignocaine) may increase the blood levels of lidocaine by approximately 30%. The combination should be avoided. When taken together with propranolol, the following may result in a change in the blood level of themselves, propranolol or both:- calcium channel blockers e.g. verapamil, diltiazem, isradipine, lacidipine, nisoldipine antipsychotics e.g. chlorpromazine, thioridazine theophylline quinidine hydralazine propafenone rifampicin warfarin cimetidine alcohol

Other medicines containing the same active ingredients

Inderal Tablets

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