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People taking anticoagulant medicines used to prevent the blood clotting, eg warfarin, should not take aspirin to relieve pain, inflammation or fever. This is because aspirin can irritate the stomach lining, as well as increasing the effects of warfarin, both of which increase the likelihood of bleeding.
There may be an increased risk of bleeding if aspirin is taken with 'blood-thinning' (antiplatelet) medicines such as clopidogrel or dipyridamole.
There may also be an increased risk of bleeding if aspirin is taken in combination with venlafaxine, duloxetine, or SSRI antidepressants such as fluoxetine or paroxetine.
There may be an increased risk of bleeding or ulceration of the stomach or intestines if aspirin is taken with corticosteroids, eg prednisolone, dexamethasone.
There may be an increased risk of side effects if aspirin is taken with other non-steroidal anti-inflammatory drugs (NSAIDs), eg ibuprofen, diclofenac, indometacin. For this reason, this medicine should not be taken with any other NSAID.
Aspirin reduces the rate at which the body can remove the medicine methotrexate. The two should not usually be used together.
There may be an increased risk of side effects if aspirin is taken with acetazolamide.
Other medicines containing the same active ingredients
| Anadin original | Beechams powders |