How does it work?
This medicine contains the active ingredient diflucortolone valerate, which is a type of medicine known as a corticosteroid (or steroid). Corticosteroids are hormones that are produced naturally by the adrenal glands, and have many important functions, including control of inflammatory responses.
Diflucortolone is a synthetic corticosteroid and is used to decrease inflammation in the skin. When applied to the skin it is absorbed into the skin cells. Here it works by preventing the release of certain chemicals from the cells. These chemicals are important in the immune system, and are released as a result of allergy or irritation. They cause blood vessels to widen, resulting in the affected area of skin becoming red, swollen, itchy and painful, such as is seen in dermatitis or eczema. By decreasing the release of these chemicals in the skin, diflucortolone reduces inflammation and relieves itch.
There is a range of potencies of corticosteroids applied to the skin. Diflucortolone 0.3% is classed as a very potent corticosteroid. It is prescribed to treat severe inflammatory skin disorders that have not responded to weaker corticosteroids.
Diflucortolone 0.3% is available as an oily cream or ointment. The oily cream is less greasy than the ointment and is suitable for skin that is neither weeping nor very dry. The ointment is more greasy and is suitable for very dry skin conditions. Both provide a layer of oil on the surface of the skin that helps to prevent water evaporating, thereby reducing dryness and scaling.
What is it used for?
Inflammatory skin disease known as discoid lupus erythematosus (DLE)
Psoriasis
Severe eczema
Severe inflammatory skin disorders
Skin disorder causing a flat, itchy, violet rash, usually on the wrists, shins, lower back and genitals (lichen planus)
Thickened skin rash caused by excessive scratching to relieve itching (neurodermatitis)
Warning!
If corticosteroids are used long-term, on large areas of skin, raw skin, skin folds, or under airtight dressings (including nappies) they are absorbed into the body more. This increases the risk of local side effects such as skin thinning, and those on other parts of the body, such as a decrease in the production of natural hormones by the adrenal glands. For this reason, continuous, long-term use of this medicine should be avoided wherever possible, particularly in children and on large areas of skin. You should only use airtight dressings over the affected area if instructed by your doctor.
This preparation is for external use only.
If you have been prescribed this medicine to treat psoriasis you should have regular check-ups with your doctor. This is because although corticosteroids may be useful for psoriasis in the short-term, they can sometimes make psoriasis worse, and may cause the condition to relapse into generalised pustular psoriasis after the treatment is stopped.
This medicine should be applied thinly and evenly to the affected area(s).
Avoid contact of this medicine with the eyes and the moist membranes lining the inside of certain parts of the body, eg mouth, nasal passages (mucous membranes). Rinse with cold water if accidental contact occurs.
Wash your hands thoroughly after applying this medicine, unless the hands are the area being treated.
Do not use this medicine for longer than seven days unless directed by your doctor.
Consult your doctor if your skin becomes infected during treatment, as you may need to stop using this medicine and start treatment with antibiotics.
Do not use this medicine on the face.
Use with caution in
Children
Psoriasis
Not to be used in
Acne rosacea
Acne vulgaris
Children under four years of age
Infections of the skin with viruses (eg Herpes simplex, chickenpox), fungi (eg thrush, ringworm, athlete's foot) or bacteria (eg impetigo)
Inflammatory rash around the mouth (perioral dermatitis)
Itching around the back passage and genitals
Nappy rash
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
This medicine should not be used during pregnancy unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings, or for prolonged periods of time. Consult your doctor for further information.
This medicine should not be used during breastfeeding unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings or for prolonged periods of time. If it is applied to the breasts it should be washed off carefully before breastfeeding and then reapplied afterwards.
Label warnings
This medication is to be spread thinly and sparingly on the skin.
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