Neotigason

How does it work?

Acitretin is a type of medicine known as a retinoid. Retinoids have a structure similar to vitamin A and are involved in the normal growth of skin cells. Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

What is it used for?

Palmo-plantar pustular psoriasis (pustular psoriasis affecting the palms of the hands and soles of the feet)

Severe congenital ichthyosis

Severe Darier's disease

Severe psoriasis

Warning!

Avoid exposure to sunlight or sunlamps while using this medicine, as it increases the sensitivity of your skin. If exposure to sunlight cannot be avoided, use protective measures such as sun-creams or protective clothing.

People taking this medicine should have regular blood tests.

Effective contraception is required for 1 month before treatment, during treatment, and for at least two years after stopping treatment.

Patients should not donate blood during and for at least one year after treatment.

Use with caution in

Children

Not to be used in

Acitretin is contraindicated in women of child bearing potential unless pregnancy is excluded before treatment starts and effective contraception is used during treatment and for two years after stopping treatment.

Breastfeeding

Decreased kidney function

Decreased liver function

Known sensitivity or allergy to any ingredient

Pregnancy

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should not be used during pregnancy as it may be harmful to the unborn baby. Seek medical advice from your doctor.

Significant amounts of this medicine may pass into breast milk. It should not be used by breastfeeding mothers. Discuss this with your doctor.

Label warnings

Follow the printed instructions you have been given with this medication.

Take this medication with or after food.

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