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Migril

Health and Nutrition > Medicines > M

Health Centres - Migril



How does it work?

This medicine contains three active ingredients, ergotamine tartrate, cyclizine hydrochloride and caffeine citrate. It is used for the relief of an acute migraine attack. The cause of migraine is not fully understood but it appears the widening of blood vessels in the brain. This may involve the chemical serotonin. Ergotamine temporarily constricts blood vessels around the skull and throughout the body. It is most effective if taken at the first sign of a migraine attack. Cyclizine is an anti-emetic which acts on the vomiting centre of the brain. It is included in this medicine to treat the nausea and vomiting associated with migraine. Caffeine is traditionally included as it is believed to enhance the analgesic effects.

What is it used for?

- Treatment of migraine

Warning!

- This medicine should not be used for the prevention of this condition, only in the treatment.
- This medicine may cause drowsiness. If affected do not drive or operate machinery.
- Ergotamine-containing compounds may preciptitate arterial constriction. If symptoms of arterial insufficiency develop (coldness, numbness or tingling of the extremities) the medicine should be discontinued immediately. Repeated doses have occasionally been associated with renal artery spasm and loss of renal function.

Use with caution in

- Alcohol intake
- Anaemia
- Hyperthyroidism
- Infection of the blood or body tissues with pus-forming or other pathogenic organisms (sepsis)
- Severe inflammation of the liver, with a rapid onset and of short duration (acute hepatitis)

Not to be used in

- Angina pectoris
- Breastfeeding
- Coronary artery disease
- Cramping pain in the calf muscles brought on by exercise, due to narrowing of the arteries in the calves
- Disease involving the blood vessels
- High blood pressure
- Known sensitivity or allergy to any ingredient
- Narrowing of the blood vessels in the hands, causing numb and painful fingers (Raynaud's disease)
- Poor blood flow to the extremities (hands and feet)(peripheral vascular insufficiency).
- Pregnancy

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

- This medicine should not be used in pregnancy. Seek medical advice from your doctor.
- This medicine should not be used by breastfeeding mothers. Discuss this with your doctor.

Label warnings

- Refer to the printed instructions for maximum weekly intake.
- This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.



The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care or attention by a qualified practitioner. The materials in this web site cannot and should not be used as a basis for diagnosis or choice of treatment. Conditions for use Powered by netdoctor
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