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- Disturbances of the gut such as nausea, vomiting, diarrhoea or abdominal pain
- Fever (pyrexia)
- Headache
- Inflammation of the lining of the mouth (stomatitis)
- Mouth ulcers
- Loss of appetite
- Dizziness
- Difficulty in sleeping (insomnia)
- Cough
- Low blood sodium level (hyponatraemia)
- Low red blood cell count (anaemia)
- Decrease in the number of a type of white blood cell (neutrophil) in the blood (neutropenia)
- Hair loss (alopecia)
- Allergic reactions such as rash, or severe swelling of lips, face or tongue (angioedema)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
How can this medicine affect other medicines?
It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines in combination with this one, to ensure that the combination is safe.
The amount of atovaquone in the blood may be reduced by the following medicines and these could make it less effective at preventing and treating malaria:
- metoclopramide
- rifampicin and rifabutin (these medicine are not recommended for people taking Malarone)
- tetracycline.
Atovaquone may decrease the blood level of the anti-HIV medicine indinavir.
The antacid magnesium trisilicate may decrease the absorption of proguanil from the gut if it is given at the same time of day. If both medicines are needed their doses should be separated by at least three hours.
Other medicines containing the same active ingredients
| Malarone paediatric |