Health Centres - Lopid
How does it work?
This medicine contains the active ingredient gemfibrozil, which is a type of medicine known as a fibrate. It works by reducing the production of fats (lipids) by the liver. These lipids include cholesterol and triglycerides.
What is it used for?
-
High levels of fats
-
Prevention of coronary heart disease in men aged 40-55 with hyperlipidaemia that has not responded to diet or other measures
- This medicine may very rarely have side effects on the muscles. For this reason you should inform your doctor immediately if you experience any muscular symptoms such as pain, tenderness, cramps, or weakness while taking this medicine, particularly if it is accompanied by a fever or feeling generally unwell. Your doctor may need to check for side effects on the muscles by taking a blood test to measure the level of a compound called creatinine kinase in your blood. If this is the case, the test should not be done following strenuous exercise.
- This medicine is not recommended for use in children.
- You should should continue eating a cholesterol-lowering diet during treatment with this medicine. Discuss this with your doctor.
- If your doctor considers that an adequate response has not been achieved within three months of treatment with this medicine, your doctor may ask you to stop taking this medicine.
- Blood tests to monitor liver function and levels of blood components should be performed before starting treatment with this medicine, and regularly for the first year of treatment.
- Blood lipid levels should be monitored before starting and regularly throughout treatment.
- Consult your doctor if you experience troublesome pain in the upper part of your stomach, or yellowing of the skin (jaundice) while taking this medicine.
Use with caution in
- Decreased kidney function
-
Diabetes
- History of liver disease
-
Hypothyroidism
- Individuals who consume large quantities of alcohol
- Kidney disease
Not to be used in
-
Alcoholism
-
Breastfeeding
- Decreased liver function
-
Gall stones
- Pregnancy
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- The safety of this medicine during pregnancy has not been established, therefore it should not be used by pregnant women. Consult your doctor.
- There is no information available about the safety of this medicine during breastfeeding. For this reason, the manufacturer states that it should not be used during breastfeeding. Seek medical advice from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
- Headache
- Rash
- Itching (pruritus)
- Blurred vision
- Excess gas in the stomach and intestines (flatulence)
- Impotence
- Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain
- Inflammation of the pancreas (pancreatitis)
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Yellowing of the skin and eyes (jaundice)
- Severe swelling of lips, face or tongue (angioedema)
- Dizziness
- Rapid and irregular beating of the heart (atrial fibrillation)
- Muscle breakdown (rhabdomyolysis)
- Muscle pain (myalgia) and weakness (myasthenia)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
